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Disclosures: This material is for informational purposes only. The information and data herein are believed to be reliable; however, their accuracy and completeness is not guaranteed by Morgan Stanley Smith Barney LLC ("Morgan Stanley") and providing you with this information is not to be considered a solicitation on our part with respect to the purchase or sale of any securities, investments, strategies or products that may be mentioned. In addition, the information and data referenced is as of the date of the material and subject to change without notice. Past performance is not a guarantee of future results.

Morgan Stanley, its affiliates and Morgan Stanley Financial Advisors and Private Wealth Advisors do not provide tax or legal advice. Clients should consult their tax advisor for matters involving taxation and tax planning and their attorney for matters involving trust and estate planning, charitable giving, philanthropic planning and other legal matters.

University Hospital of Cleveland, OH is a client of Morgan Stanley. It is not known whether the client approves of Morgan Stanley or the advisory services provided. Nothing in this material is intended to imply any other affiliation, sponsorship, endorsement, approval, investigation, verification or monitoring of the Harrington Discovery Institute, University Hospital of Cleveland, OH. or any other entity referenced in this material.

The Morgan Stanley Global Impact Funding Trust (GIFT), Inc. is an organization described in Section 501(c) (3) of the Internal Revenue Code of 1986, as amended. Morgan Stanley Global Impact Funding Trust (GIFT) is a donor-advised fund. Morgan Stanley provides investment management and administrative services to Morgan Stanley GIFT.

While we believe that Morgan Stanley GIFT Cures^SM provides a valuable philanthropic opportunity, contributions to Morgan Stanley GIFT Cures^SM are not appropriate for everyone. Other forms of charitable giving may be more appropriate depending on a donor’s specific situation. Of critical importance to any person considering making a donation to Morgan Stanley GIFT is the fact that any such donation is an irrevocable contribution.

Back office administration provided by Ren, an unaffiliated charitable gift administrator.

Morgan Stanley Smith Barney LLC, Member SIPC